SAPHO syndrome includes a variety of inflammatory bone disorders that may be associated with skin changes. SAPHO stands for Synovitis-Acne-Pustulosis-Hyperostosis Osteomyelitis.
An entity initially known as Chronic Recurrent Multifocal Osteomyelitis (CRMO) was first described in 1972. The term SAPHO was
Treatment is with NSAIDs, steroids, methotrexate or Enbrel.
References: Original post by Clinical Cases
Round 7: Synovitis-Acne-Pustulosis-Hyperostosis osteomyelitis syndrome (SAPHO). Johns Hopkins University School of Medicine.
SAPHO syndrome, from Wikipedia, the free encyclopedia.
